I have a 36 Navy and a 44 Dragoon.Awhile back had to take out several sick sheep and used the revolvers as an experiment.They are not powerfull weapons.Noted some deflections off bone even up close.As you know the Colt uses the hammer as a back site and not good for long distance accuracy even tho the ball does spin.
As the previous poster said,up close and a hit or two in the right place and you may live to fight another day.