Find a grave lists Annie as his wife. See her on the 1880 census

John A. Comfort
in the 1880 United States Federal Census
Name: John A. Comfort
Age: 43
Birth Year: abt 1837
Birthplace: Mississippi
Home in 1880: Attala, Mississippi
Race: White
Gender: Male
Relation to Head of House: Self (Head)
Marital Status: Married
Spouse's Name: Annie M. Comfort
Father's Birthplace: New York
Mother's Birthplace: Tennessee
Occupation: Farmer
Household Members:
Name Age
John A. Comfort 43
Annie M. Comfort 27
Jennie W. Comfort 5
Annie M. Comfort 3
John W. Comfort 1